Millions of people who live with chronic pain hear some version of the same dismissal: the scan looks fine, so the problem ...

NEW IBS research highlights persistent pain treatment gaps and points to peripheral nerve targets for future, safer therapies ...

Author Rachel Zoffness breaks down why we have chronic pain and how science shows that it’s all in our head ...

Placebo effects, in which patients experience relief without therapeutic treatment, increasingly have been considered as potentially powerful clinical treatments for ailments such as depression and ...

This article examines emerging non-opioid strategies for chronic pain, from targeted ion-channel drugs and anti-inflammatory ...

Using sensors and a light-activated drug, the team mapped neural pathways used by endogenous opioids to send pain relief ...

How does the placebo effect work? A new study identifies the vlPAG brain region and endogenous opioid signaling as the keys to expectancy-driven pain relief.

Giant migrating contractions (GMCs) are powerful waves of colonic movement that propel intestinal contents toward the anus ...