Morning Overview on MSN

IDEAYA-Servier eye cancer drug hits trial goal, clearing path to FDA filing

A closely watched clinical trial testing a new two-drug combination against metastatic uveal melanoma, the deadliest form of ...
IEEE

Pan-protein Design Learning Enables Task-adaptive Generalization for Low-resource Enzyme Design

Abstract: Computational protein design (CPD) offers transformative potential for bioengineering, but current deep CPD models, focused on universal domains, struggle with function-specific designs.
eLife

Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation

EM, biochemical, and cell-based assays to examine how Gβγ interacts with and potentiates PLCβ3. The authors present evidence for multiple Gβγ interaction surfaces and argue that Gβγ primarily enhances ...