The Science Advances publication details Cellgorithmâ„¢, a CRISPR-based technology that gives researchers greater control over gene activity and sets the stage for future applications in stem cell ...
The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...
A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the ...
Syntax Bio, a synthetic biology company programming the next generation of cell therapies, has published new research in Science Advances detailing the company's CRISPR-based Cellgorithm technology, ...
For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...
Scientists have discovered how two transcription factors form a reciprocal regulatory circuit that controls T-cell exhaustion ...
Just before the pandemic took center stage in 2020, scientists at a T cell memory conference convened to discuss a less than traditional topic: nomenclature. Prior to the event, the workshop ...
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