A phase 2/3 trial of Ideaya Biosciences and Servier’s eye cancer candidate has hit its primary endpoint, teeing up a filing for accelerated FDA approval in the second half of th ...
The company is hoping to seek accelerated approval in first-line HLA-A*A2:01-negative metastatic uveal melanoma based on data ...
A closely watched clinical trial testing a new two-drug combination against metastatic uveal melanoma, the deadliest form of ...
EM, biochemical, and cell-based assays to examine how Gβγ interacts with and potentiates PLCβ3. The authors present evidence for multiple Gβγ interaction surfaces and argue that Gβγ primarily enhances ...