Structure Therapeutics: The Oral Obesity Inflection, Best-In-Class Efficacy Meets Biased-Agonism Safety Moat

ACCG-2671 is an oral small molecule amylin receptor agonist which acts through complementary satiety pathways in the ...
AHA/ASA Journals

Olfactory Receptor Activation Reduces Platelet Reactivity and Arterial Thrombosis Through Actin Cytoskeleton Remodeling

BACKGROUND: Despite antiplatelet therapy, some patients remain at high ischemic risk because of drug nonresponsiveness or high residual platelet reactivity). We aimed to target an orphan platelet GPCR ...

'Hamelin Assay' traces molecular mechanisms that may guide cancer cell spread

Metastases are a key problem in many types of cancer. As descendants of the primary tumor, they can grow in other organs ...
Nature

Bryden Le Bailly

Bryden is a Senior Editor at Nature, handling chemistry and biology publications manuscripts, looking specifically at research in the areas of chemical biology, ion channel biology, GPCRs and origin ...