Humans have about 3 billion DNA bases in their genetic makeup. However, most of it does not encode for protein.

Anti-cancer drugs often fail, but a new discovery about how two key proteins interact with DNA is changing that, serving as a ...

Not all parts of our genetic code are equal, even when they appear to say the same thing. Scientists have discovered that ...

For more than a decade, a class of drugs called BET inhibitors has been tested in cancer trials with high expectations. The biology looked promising. Many cancers depend on oncogenes that "Bromo- and ...

DNA inside the nucleus is not packed as a rigid regular fiber-linker histone H1 dynamically binds and loosely "glues" ...

Cancer drugs known as BET inhibitors once looked like a breakthrough, but in real patients they’ve often fallen short. New ...

Changing just a single base in a specific DNA region of a female mouse embryo led to the development of male reproductive organs. A research team led by Nitzan Gonen at Bar-Ilan University in Israel h ...

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" ...

Every cell in your body faces the same engineering puzzle: how to cram roughly two meters of DNA into a nucleus just a few ...