This month’s story comes from the Bloom lab using their signature deep mutational scanning technique to identify mutations in the surface protein of Lassa virus -called glycoprotein- that escape ...
Researchers have developed EVE-Vax, a computational design tool that creates synthetic SARS-CoV-2 spike proteins mimicking future immune-evading variants. These designed proteins enable early ...
Broadly neutralizing antibodies (bNAbs) are among the most promising new treatments for HIV, offering the potential to forego traditional daily doses of antiretroviral drugs. In one recent clinical ...
An electronic 96-channel pipette was one of the tools used to scale up and allow the teamto perform over 7,000 parallel experiments that uncovered more than 100 bNAb escapemutations across 15 viral ...
When the COVID-19 pandemic first began, we saw how quickly the SARS-CoV-2 virus evolved. New variants emerged with mutations that increased transmissibility or helped the virus evade our immune ...