Programmable recombinases let one cell produce multiple fates in preset ratios, enabling controlled division of labor, ...
The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...
A cluster of recent studies has sharpened the scientific picture of how T cells switch on, tracking the molecular signals ...
CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...