A Snakemake-based pipeline called Pipeasm automates key steps of genome assembly, from raw read trimming through scaffolding and contamination screening, and the authors report up to 99.6% BUSCO ...

Sequence analysis is a cornerstone of modern bioinformatics, encompassing the computational exploration of biological sequences—be they DNA, RNA or proteins—to reveal insights into structure, function ...

What is Third-Generation Sequencing? Third-generation sequencing, also known as long-read sequencing, refers to the latest advancements in DNA sequencing technologies that enable the analysis of ...

Phylogenetic analysis and DNA sequence representation are foundational pillars in modern molecular biology and bioinformatics. These approaches not only facilitate the reconstruction of evolutionary ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

The Advances in Genome Biology and Technology (AGBT) meeting celebrated its 25 th anniversary in sunny Marco Island, Florida, with the customary mix of big name speakers addressing researchers and ...

Researchers present a comprehensive review of frontier AI applications in computational structural analysis from 2020 to 2025 ...

Unless you’ve been hiding under a rock for the past few years, you know next-generation DNA sequencing is all the rage. The technique has gone from gee-whiz to practically routine in the five years ...

In a single experiment, scientists can decipher the entire genomes of many patient samples, animal models, or cultured cells. To fully realize the potential to study biology at this unprecedented ...