Rheumatoid arthritis is a chronic autoimmune disease that affects millions of people worldwide. This disease prompts the immune system to mistakenly attack body tissues, particularly joints, leading ...

When the cell begins to broadcast their existence through signaling on a frequency different from that of the immune system, they are, literally speaking, “looking for trouble”. As explained in the ...

One genetic mutation may transform the way we treat rheumatoid arthritis, a disease that will affect an estimated one percent of the world. York University researchers have identified a mutation in ...

TAM receptors are key in immune regulation and inflammation resolution, with Axl and MerTK offering protective benefits in RA, while Tyro3 may worsen inflammation. Soluble TAM receptors (sTAMs) could ...

Researchers said the findings strongly support the hypothesis that these bacteria, initially colonizing gum tissue, somehow drive the development of rheumatoid arthritis, at least in some patients.

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, but they don't work for up to 4 of every 10 patients. New research led by ...

Macrophages, as integral components of the immune system, exhibit diverse roles due to their ability to assume various ...