A new review links three forces shaping osteoarthritis: mechanical stress, integrin signaling, and integrin endocytosis. The ...

MALVERN, Pa., Jan. 16, 2025 (GLOBE NEWSWIRE) -- Ocugen, Inc. (OCGN), a biotechnology company focused on discovering, developing, and commercializing novel gene and cell therapies, biologics, and ...

Antibody Therapeutics Inc. has disclosed integrin receptor antagonists reported to be useful for the treatment of pulmonary fibrosis, renal fibrosis and hepatic fibrosis.

Inflammation drives TGFβ1 activation via the αvβ6 integrin-mechanotransduction pathway in human skin. Transforming growth factor β (TGFβ) is a critical regulator of skin home ...

Atherosclerosis represents a chronic inflammatory disease characterized by the accumulation of lipid-laden macrophage foam cells within arterial walls, serving as the underlying pathological basis for ...